Treating Acne: A Pharmacological Approach

This 2-hour CE course provides healthcare professionals with a comprehensive review of pharmacologic therapies used in the management of acne vulgaris. Grounded in current clinical guidelines and dermatologic evidence, the course covers both first-line and adjunctive treatment options for patients across varying age groups and acne severity levels. It is designed for clinicians in primary care, dermatology, pediatrics, and women’s health settings who play a central role in diagnosing and managing acne.

The course begins with an overview of acne pathophysiology, including the roles of follicular hyperkeratinization, increased sebum production, Cutibacterium acnes proliferation, and inflammation. Participants will learn to assess acne severity using standardized grading scales and to individualize therapy based on lesion type, patient characteristics, and risk for scarring or hyperpigmentation.

Topical agents such as retinoids, benzoyl peroxide, antibiotics, and azelaic acid are explored in detail, with guidance on their mechanisms of action, appropriate application, and common adverse effects. Systemic therapies—including oral antibiotics, hormonal treatments (such as combined oral contraceptives and spironolactone), and isotretinoin—are reviewed, with emphasis on appropriate indications, monitoring requirements, and management of adverse effects.

Special considerations are addressed for adolescent patients, pregnant individuals, and patients with treatment-resistant or nodulocystic acne. The course also highlights the importance of medication adherence, patient education, and maintenance therapy to achieve long-term skin clearance and reduce recurrence.

Learning Objectives:

Upon successful completion of this course, participants will be able to:

• Describe the pathophysiological mechanisms underlying acne development.
• Identify appropriate pharmacologic agents for varying severities and types of acne.
• Compare topical and systemic treatment options based on clinical indications and patient factors.
• Recognize adverse effects and monitoring considerations for commonly prescribed acne medications.
• Develop individualized treatment plans that support adherence and minimize resistance.
• Counsel patients on safe and effective use of pharmacologic therapies for acne management.

Completion Requirements:

To complete this CE course and receive full credit, participants must:

• Register for the course.
• Complete all course materials and content modules.
• Complete the post-test with a passing score of 70% or higher.
• Submit a completed course evaluation.

Note: Some courses may include additional assignments or case-based assessments.

Important Disclosures:

• Conflict of Interest: The course planners, authors, and presenters have no financial or commercial conflicts of interest related to this educational activity.
• Commercial Support:This course has not received sponsorship or financial support from commercial entities.
• Non-Endorsement: Approval of this course as a continuing education activity does not imply endorsement of any products, services, or companies mentioned within the content.
• Off-Label Product Use: Some treatment strategies discussed may involve off-label use of medications; these instances will be clearly identified within the content.